Japanese scientists have said that regular use of coffee improves memory and attention, Report informs, citing Springer.
The study was conducted by researchers from the University of Tsukuba. After 30 days of oral administration of TG at a dose of 5 mg/kg/day, the mice were trained in Morris Water Maze task.TG-treated SAMP8 mice exhibited significant improvement in the parameters of escape latency, distance moved, and annulus crossing index. Next, the scientists performed whole-genome transcriptome profiling of the mouse hippocampus using microarrays. Gene ontology analyses showed that a wide range of biological processes, including nervous system development, mitochondrial function, ATP synthesis, and several signaling pathways related to inflammation, autophagy, and neurotransmitter release, were significantly enriched in TG-treated SAMP8 compared to nontreated.